扶正蠲痹汤内服外熏联合常规西药治疗膝骨性关节炎的效果

Effect of internal and external fume of Fuzheng Juanbi decoction combined with conventional western medicine on knee osteoarthritis

目的探讨扶正蠲痹汤内服外熏联合常规西药治疗膝骨性关节炎(KOA)患者的临床疗效。方法选取我院2013年5月至2017年3月医院收治的KOA患者120例为研究对象,根据采用治疗方案的不同将其分为观察组和对照组,各60例。对照组患者给予常规西药进行治疗,观察组在此基础上给予扶正蠲痹汤内服外熏疗法。比较两组患者的临床疗效、治疗前后视觉模拟评分(VAS)、膝关节评分(Lysholm)、WOMAC僵硬度评分及血清红细胞沉降率(ESR)、类风湿因子(RF)、C反应蛋白(CRP)水平。结果观察组患者的治疗总有效率为98.33%,明显高于对照组的83.33%(P<0.05)。治疗后,两组患者的VAS及WOMAC僵硬度评分均明显降低,Lysholm评分明显升高,且观察组优于对照组(P<0.05)。治疗后,两组患者的血清ESR、RF及CRP水平均明显降低,且观察组低于对照组(P<0.05)。结论扶正蠲痹汤内服外熏联合常规西药治疗KOA患者疗效确切,可明显缓解患者膝关节疼痛,改善膝关节功能,降低晨起僵硬程度,减轻炎症反应,促进病情恢复,值得临床推广。

Objective To study the effect of internal and external fume of Fuzheng Juanbi decoction combined withconventional western medicine on knee osteoarthritis （KOA）. Methods A total of 120 patients with KOA admitted in ourhospital from May 2013 to March 2017 were selected as the research objects. According to the different treatment schemes,the patients were divided into observation group and control group, with 60 cases in each group. The control group wastreated with conventional western medicine, while the observation group was treated with internal and external fume ofFuzheng Juanbi decoction combined with conventional western medicine. The clinical efficacy, visual analogue score （VAS）,knee joint score （Lysholm）, WOMAC stiffness score and serum erythrocyte sedimentation rate （ESR）, rheumatoid factor （RF）and C-reactive protein （CRP） levels before and after treatment were compared between the two groups. Results The totaleffective rate of treatment in the observation group was 98.33%, which was significantly higher than 83.33% in the controlgroup（P〈0.05）. After treatment, the VAS scores and WOMAC stiffness scores of both groups significantly reduced, and theLysholm scores significantly increased, and those of the observation group were better than the control group（P〈0.05）. Aftertreatment, the levels of serum ESR, RF and CRP in both groups significantly decreased, and those in the observation groupwere lower than the control group（P〈0.05）. Conclusion Internal and external fume of Fuzheng Juanbi decoction combinedwith conventional western medicine on KOA has curative effect, which can obviously relieve patients＇ knee joint pain,improve the function of knee joint, reduce the degree of morning stiffness, decrease inflammation and promote diseaserecovery. It is worthy of clinical promotion.