3.0T心脏磁共振对正常汉族中国人左心室半定量参数的研究

A Study of Semi-Quantitative Parameters for the Left Ventricule in Normal Han Chinese: Evaluated by 3.0T Cardiac Magnetic Resonance

目的研究正常汉族中国人的左心室半定量参数[二尖瓣环收缩期位移（MAPSE）和左心室长轴应变（LAS）]。方法采用3. 0 T心脏磁共振（CMR）的稳态自由进动（SSFP）序列对纳入的100名正常汉族志愿者进行图像采集,测量其左心室功能参数和半定量参数,并分析左心室半定量参数与性别、年龄以及左心室射血分数（LVEF）的关系。结果左心室半定量参数在性别间差异无统计学意义（P〉 0. 05）。MAPSE-mid和MAPSE-lat与年龄呈负相关（P 〈0. 05）,而LAS-mid、LAS-lat、LAS-sep、MAPSE-sep与年龄无显著相关性（P〉 0. 05）。MAPSE-sep、LAS-mid、LAS-sep与LVEF均呈正相关（P 〈0. 05）,而MAPSE-mid、MAPSE-lat、LAS-lat与LVEF不存在相关性（P〉0. 05）。结论左心室半定量参数无性别间差异,其部分指标可能与年龄和LVEF有关。

Objective To study the left ventricular semi-quantitative parameters including mitral annular plane systolic excursion（ MAPSE） and long axis strain（ LAS） with 3. 0 T Cardiac magnetic resonance（ CMR）. Methods 3. 0 T CMR with steady state free precession（ SSFP） was performed on one hundred healthy Chinese Han volunteers. The left ventricular function parameters and semi-quantitative parameters were acquireed,and the relationship between the left ventricular semi-quantitative parameters and the sex,age and left ventricular ejection fraction（ LVEF） were also analyzed. Results There was no significant difference in left ventricular semi-quantitative parameters between men and women（ P〉0. 05）.The LAS-mid,LAS-lat,LAS-sep,MAPSE-sep parameters each had a negative correlation with the age（ P〉0. 05）,whereas there was no significant relationship between the LAS-mid,LAS-lat,LAS-sep,MAPSE-sep parameters and the age,respectively（ P〉0. 05）. The MAPSE-sep,LAS-mid,LAS-sep parameters each had a negative correlation with the LVEF（ P〉0. 05）,whereas there was no significant relationship between MAPSE-mid,MAPSE-lat,LAS-lat and the LVEF（ P〉0. 05）.Conclusion There was no significant difference in left ventricular semi-quantitative parameters between men and women,and some of the parameters may be related to the age and LVEF.