摘要
目的:探讨早期肠内营养联合补充性肠外营养在创伤患者中的应用效果。方法:将选取的120例严重创伤患者随机分为2组,观察组给予早期肠内营养联合补充性肠外营养,对照组给予肠内营养,观察并比较两组患者恢复经口饮食时间、患者营养状况、临床结局情况。结果:观察组患者恢复经口饮食时间显著短于对照组,差异有统计学意义(P <0. 05);营养支持2w后,观察组的血清白蛋白、血清总蛋白、血红蛋白、视黄醇结合蛋白、转铁蛋白均显著高于治疗前,差异有统计学意义(P <0. 05);对照组的血红蛋白、视黄醇结合蛋白、转铁蛋白均显著高于治疗前,差异有统计学意义(P <0. 05),而血清白蛋白、血清总蛋白在治疗前后没有显著差异(P> 0. 05);营养支持2w后,观察组的血清白蛋白、血清总蛋白、血红蛋白、转铁蛋白显著高于对照组,差异有统计学意义(P <0. 05),两组的视黄醇结合蛋白差异不显著(P> 0. 05);两组患者的感染、急性呼吸窘迫综合征发生率差异不显著(P>0. 05),两组患者的机械通气时间及ICU治疗时间差异不显著(P> 0. 05)。结论:早期肠内营养联合补充性肠外营养有利于严重创伤患者尽早恢复经口饮食,有利于改善患者营养状态,这种营养方式不会对患者临床结局产生不利影响。
Objective To investigate the effect of early enteral nutrition combined with supplemental parenteral nutrition in trauma patients.Method Totally 120 patients with severe trauma were randomly divided into two groups.The observation group was given early enteral nutrition combined with supplementary parenteral nutrition,and the control group was given enteral nutrition.The oral recovery time,nutritional status and clinical outcomes were observed and compared between the two groups.Result The oral recovery time of the observation group was significantly shorter than that of the control group,with a significant difference ( P 〈0.05).After 2 weeks of nutritional support,the serum albumin,serum total protein,hemoglobin,and retinol binding protein were observed in the observation group was significantly higher than before treatment,and the difference was statistically significant ( P 〈0.05).The levels of hemoglobin,retinol binding protein,and transferrin in the control group were significantly higher than before treatment,and the difference was statistically significant ( P 〈0.05).Serum albumin and serum total protein were not significantly different before and after treatment( P 〉0.05).2 weeks after nutritional support,serum albumin,serum total protein,hemoglobin and transferrin were significantly higher in the observation group than in the control group( P 〈0.05).There was no significant difference in retinol binding protein between the two groups( P 〉0.05).There was no significant difference in the incidence of infection and acute respiratory distress syndrome between the two groups (P 〉0.05).Both groups had mechanical ventilation time and ICU treatment,the time difference was not significant( P〉0.05).Conclusion Early enteral nutrition combined with supplementary parenteral nutrition is beneficial for patients with severe trauma to resume oral diet as soon as possible,which is beneficial to improve the nutritional status of patients.This kind of nutrition will not adversely affect the clinical outcome of patients.
作者
冯蕾
张世瑶
曹静
FENG Lei;ZHANG Shi-yao;CAO Jing(Emergency Trauma Center,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,China;Clinical Nutrition,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,China)
出处
《中国食物与营养》
2018年第11期78-80,共3页
Food and Nutrition in China
基金
新疆维吾尔自治区科研基金(项目编号:2015211C073)
关键词
胃肠内营养
胃肠外营养
严重创伤
疗效
gastrointestinal nutrition;parenteral nutrition;severe trauma;efficacy