医院获得性败血症住院费用、住院时间及死亡率的回顾性研究

A Retrospective Study of Hospitalization Costs,Length of Hospital Stay and Mortality of Hospital Acquired Sepsis

目的探讨医院获得性败血症对患者住院费用、住院时间及患者死亡情况的影响,为进一步采取针对性的感染控制措施,控制疾病负担提供科学依据。方法回顾性调查2016年1月1日—2017年6月30日期间广州市某三甲医院确诊为医院获得性败血症的患者临床资料,并按相关标准设立1∶1对照,比较两组间住院费用、住院时间及死亡率差异。结果共纳入病例67例,匹配对照67例。病例组中位住院费用55 534. 59元,对照组中位住院费用31 874. 03元;病例组中位住院时间17 d,长于对照组的14 d,差异均有统计学意义。病例组死亡率28. 4%,高于对照组6. 0%,两组差异有统计学意义。结论医院获得性败血症的发生,增加了患者的经济负担,延长了患者住院时间,并使患者死亡风险提高。加强对医院获得性败血症的监测,提高败血症诊疗水平非常重要。做好感染防控,是控制医院获得性败血症的重要手段。

Objective To investigate the impact of hospital-acquired sepsis on hospitalization costs, length of stay in hospital and mortality in patients, and provide scientific evidence for further targeted infection control measures and control of disease burden. Methods A retrospective survey was conducted to investigate hospital-acquired sepsis on hospitalization costs, length of stay in hospital and mortality among the patients with acquired sepsis in a hospital in Guangzhou from January 1, 2016 to June 30, 2017, and the controls in the number determined by a ratio of 1 ∶ 1 were established according to relevant standards. We compared the two groups in hospitalization costs, length of stay and difference in mortality. Results A total of 67 cases were included in the trial, 67 controls were matched. The median hospitalization cost of the case group was 55 534.59 yuan, and the median hospitalization cost of the control group was 31 874.03 yuan. The median length of stay of the case group was 17 days, which was significantly longer than the control group （ P 〈0.05）. The mortality in the case group was significantly higher than that in the control group （28.4% vs 6.0%, P 〈0.05）. Conclusion The occurrence of hospital-acquired sepsis not only increases the economic burden on patients and prolongs the length of hospital stay, but also increases the risk of death. It is very important to strengthen the monitoring of hospital-acquired sepsis and improve our ability of diagnosis and treatment of sepsis. Preventing infection is an important method to control the morbidity of hospital acquired sepsis.