对比分析不同剂量黄体酮治疗无排卵性月经失调的效果

Comparative analysis of different doses of progesterone in the treatment of anovulatory menstrual disorder clinical effect

目的探讨分析在治疗无排卵性的月经失调患者中应用不同的黄体酮剂量临床的治疗效果。方法选取2016年3月～2018年3月于我院接受诊治的无排卵性的月经失调患者70例作为研究对象,对其采用不同的黄体酮剂量进行治疗,将其分为研究组和对照组,各35例。对照组的患者使用黄体酮的剂量为100 mg/d,研究组的患者使用黄体酮的剂量为300mg/d。对研究结果进行统计分析,对比两组患者在不同的黄体酮剂量治疗之下疗效以及发生不良反应的情况。结果经过分析对比可知,研究组的患者在临床上的治疗效果相较于对照组患者明显要好,差异有统计学意义(P<0.05),并且发生不良反应的情况相较于对照组患者也明显要好,差异有统计学意义(P<0.05)。结论在治疗无排卵性的月经失调中应用不同剂量的黄体酮临床的治疗效果有一定的差异,稍微较大的剂量效果更为明显,其发生不良反应的情况也相对较好,但是对于最合适的剂量的确定是本次研究的不足之处,也是今后研究的方向。

Objective To investigate the clinical efficacy of different doses of progesterone in thetreatment of anovulatory menstrual disorders.Methods Seventy anovulatory menstrual disorders patients whowere treated in our hospital from March 2016 to March 2018 were selected as subjects and treated with differentdoses of progesterone. Patients in the control group received 100 mg of progesterone daily,while patients inthe study group received 300 mg of progesterone daily.Statistical analysis of the results of the two groupsof patients with different doses of progesterone treatment under the clinical efficacy and adverse reactions.Results Through the analysis and comparison, the treatment effect of the study group was significantly betterthan that of the control group （P〈0.05）,and the occurrence of adverse reactions was also significantly betterthan that of the control group （P〈0.05）.Conclusion The clinical effects of different doses of progesterone inthe treatment of anovulatory menstrual disorders are different, the slightly larger doses are more obvious,andthe adverse reactions are relatively good.But the determination of the most appropriate dose is the deficiency ofthis study,and it is also the future study. The direction.