睾丸性生殖障碍——支持细胞与支持细胞综合征

Testicular reproductive disturbance—Sertoli cells and Sertoli cell syndrome

男性生殖系统的结构和功能受神经和内分泌的调节。尤其是“下丘脑—垂体—睾丸轴”的功能其完整统一,直接关系到睾丸的生精功能和精子质量。因此,在男性生殖障碍中就相应的形成睾丸前、睾丸本身与睾丸后原因。本文仅就睾丸原因叙述如下:一、睾丸功能与精子生成精子发生在睾丸的生精小管内,成人的睾丸重量为10.5～14.0g,周围被白膜包裹。

The structure and function of male reproductive system are controlled by nervous and endocrine systems.Only under the sound and perfect regulation of neuroendocrine functions,the spermatogenic cells in convoluted seminiferous tubules of testis regularly and continuously change into mature spermatozoa by a series of transformations.For the completion of spermatogenesis,participation of multiple hormones is necessary. Especially,the normal function of hypothalamus-pituitary-testis axis has direct bearing on the seminiferous function of testes and quality of sperm.In the process of spermatogenesis,Sertoli cells are the central link,and the injury of Sertoli cells is often the key factor of infertility.Therefore,in the diagnosis and treatment of in- fertility,knowledge of the physiological function of Sertoli cells and relevant disease is necessary.