摘要
骨化三醇是维生素D_3的一种最重要的活性代谢物,是维生素D_3信号生物学功能的主要执行者,与人体内多种疾病相关,其在人体内的水平也受到多种疾病的影响。本文主要综述疾病的发生发展与骨化三醇体内水平间的相互影响及其相关机制。
Calcitriol is one of the most important active metabolites of vitamin D3, which is responsible for the biological function of vitamin D3. Studies have shown that calcitriol is associated with many diseases, and its content in the human body is also affected by diseases. This review describes the function of endogenous calcitriol, and its interaction with the disease development.
作者
律立红
徐智儒
LYU Li-hong;XU Zhi-ru(State Key Laboratory of New Drug and Pharmaceutical Process,Shanghai Institute of Pharmaceutical Industry,China State Institute of Pharmaceutical Industry,Shanghai 200437;Shanghai Professional and Techniical Service Center for Biological Material Druggability Evaluation,Shanghai 200437,China)
出处
《世界临床药物》
CAS
2018年第10期699-704,共6页
World Clinical Drug