期刊文献+

抗N-甲基-M-天冬氨酸受体脑炎3例

下载PDF
导出
摘要 抗N-甲基-M-天冬氨酸(NMDA)受体脑炎是一种自身免疫性脑炎,该病主要表现为精神症状、神经症状、自主神经功能障碍及不自主运动等,可伴有发热,是一种与NMDA受体相关且对治疗有良好反应的脑炎[1],血及脑脊液中可检测到抗NMDA受体抗体阳性。目前报道中以女性患者多见,其中有大部分伴有畸胎瘤,笔者在天坛医院学习期间,见到的3例抗NMDA受体脑炎患者均为青年男性,且不伴有畸胎瘤,与以往报道常见为女性患者有所不同,现报道如下,并结合文献进行分析和讨论。
出处 《临床合理用药杂志》 2018年第31期159-160,共2页 Chinese Journal of Clinical Rational Drug Use
  • 相关文献

参考文献2

二级参考文献15

  • 1Dalmau J,Gleichman AJ,Hughes EG,et al.Anti-NMDA-receptor encephalitis:case series and analysis of the effects of antibodies.Lancet Neurol,2008,7:1091-1098.
  • 2Dalmau J,Tüzün E,Wu HY,et al.Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma.Ann Neurol,2007,61:25-36.
  • 3Lebas A,Husson B,Didelot A,et al.Expanding spectrum of encephalitis with NMDA receptor antibodies in young children.J Child Neurol,2010,25:742-745.
  • 4Ances BM,Vitaliani R,Taylor RA,et al.Treatment-responsive limbic encephalitis identified by neurophil antibodies:MRI and PET correlates.Brain,2005,128:1764-1777.
  • 5Iizuka T,Sakai F,Ide T,et al.Anti-NMDA receptor encephalitis in Japan:long-term outcome without tumor removal.Neurology,2008,70:504-511.
  • 6Ishiura H,Matsuda S,Higashihara M,et al.Response of antiNMDA receptor encephalitis without tumor to immunotherapy including rituximab.Neurology,2008,71:1921-1923.
  • 7Vincent A,Buckley C,Schott JM,et al.Potassium channel antibody-associated encephalopathy:a potentially immunotherapy responsive form of limbic encephalitis.Brain,2004,127:701-712.
  • 8Gultekin SH,Rosenfeld MR,Voltz R,et al.Paraneoplastic limbic encephalitis:neurologic symptoms,immunobiological findings and tumour association in 50 patients.Brain,2000,123:1481-1494.
  • 9Chong JY,Rowland LP,Utiger RD.Hashimoto encephalopathy.Syndrome or myth? Arch Neurol,2003,60:164-171.
  • 10Guhekin SH, Rasenfeld MR, Voltz R, et al. Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients. Brain, 2000, 123: 1481--1494.

共引文献114

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部