调强适形放疗技术在非小细胞肺癌寡转移胸部原发灶区域的临床研究

Clinical research of intensity modulated radiation therapy in chest primary tumor for oligometastatic patients with non-small cell lung cancer

在中国肺癌是恶性肿瘤的首位死亡原因,而非小细胞肺癌是肺癌最常见的组织学类型。寡转移是介于局部原发灶和广泛远处转移之间的过渡阶段,具有器官特异性。近年来许多临床研究表明,非小细胞肺癌寡转移其生物学行为不同于广泛转移的患者,预后相对较好。因此,找到有效方法改善其预后显得至关重要。本文主要探讨调强适形放疗在非小细胞肺癌寡转移治疗中的应用。

Lung cancer is the leading cause of cancer-related deaths in China and worldwide,non-small cell lung cancer（ NSCLC） is the most common pathological type of lung cancer. Oligometastasis is a transitional stage between the local primary lesion and the extensive distant metastasis,and might possess organ specificity. In recent years many clinical researches have shown that oligometastatic patients with NSCLC often have better biological behavior and better prognosis than patients with extensive lesions. So it is very necessary to find an effective treatment method for improving prognosis. This article is to explore the application of intensity modulated radiation therapy（ IMRT） in the treatment of oligometastatic NSCLC.