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白细胞介素10受体A基因变异相关炎症性肠病合并感染性肠炎 被引量:6

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摘要 腹泻是常见的临床症状。现报道1例以“腹泻、腹痛、发热”为主要表现的患儿,经完善病原学筛查及基因检测等后被诊断为白细胞介素10受体A(interleukin-10 receptor A,IL-10RA)基因变异相关IBD合并感染性肠炎,旨在理清慢性腹泻、结肠溃疡的诊疗思路,并增加对IL-10RA基因突变所致IBD的认识,以提高临床医师对该病的诊治水平。
出处 《中华消化杂志》 CAS CSCD 北大核心 2018年第11期783-786,共4页 Chinese Journal of Digestion
基金 北京协和医学院2017年教学质量工程项目(2017zlgc0110) 首都卫生发展科研专项(2016-2-40114) 中国医学科学院医学与健康科技创新工程(2016-12M-1-008)
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  • 1Martina Galatola,Erasmo Miele,Caterina Strisciuglio,Lorella Paparo,Daniela Rega,Paolo Delrio,Francesca Duraturo,Massimo Martinelli,Giovanni Battista Rossi,Annamaria Staiano,Paola Izzo,Marina De Rosa.Synergistic effect of interleukin-10-receptor variants in a case of early-onset ulcerative colitis[J].World Journal of Gastroenterology,2013,19(46):8659-8670. 被引量:7
  • 2Neil Shah,Jochen Kammermeier,Mamoun Elawad,Erik-Oliver Glocker.Interleukin-10 and Interleukin-10–Receptor Defects in Inflammatory Bowel Disease[J].Current Allergy and Asthma Reports.2012(5)
  • 3Holm H. Uhlig,Tobias Schwerd,Sibylle Koletzko,Neil Shah,Jochen Kammermeier,Abdul Elkadri,Jodie Ouahed,David C. Wilson,Simon P. Travis,Dan Turner,Christoph Klein,Scott B. Snapper,Aleixo M. Muise.The Diagnostic Approach to Monogenic Very Early Onset Inflammatory Bowel Disease[J]. Gastroenterology . 2014
  • 4Cheng Hiang Lee,Peter Hsu,Brigitte Nanan,Ralph Nanan,Melanie Wong,Kevin J. Gaskin,Rupert W. Leong,Ryan Murchie,Aleixo M. Muise,Michael O. Stormon.Novel de novo mutations of the interleukin-10 receptor gene lead to infantile onset inflammatory bowel disease[J]. Journal of Crohn’s and Colitis . 2014
  • 5Levine A,Koletzko S,Turner D,Escher JC,Cucchiara S,de Ridder L,Kolho KL,Veres G,Russell RK,Paerregaard A,Buderus S,Greer ML,Dias JA,Veereman-Wauters G,Lionetti P,Sladek M,Martin de Carpi J,Staiano A,Ruemmele FM,Wilson DC,European Society of Pediatric Gast.ESPGHAN revised porto criteria for the diagnosis of inflammatory bowel disease in children and adolescents. Journal of Pediatric Gastroenterology and Nutrition . 2014
  • 6Karin R. Engelhardt,Neil Shah,Intan Faizura-Yeop,Dilara F. Kocacik Uygun,Natalie Frede,Aleixo M. Muise,Eyal Shteyer,Serkan Filiz,Ronnie Chee,Mamoun Elawad,Britta Hartmann,Peter D. Arkwright,Christopher Dvorak,Christoph Klein,Jennifer M. Puck,Bodo Grimbacher,Erik-Oliver Glocker.??Clinical outcome in IL-10– and IL-10 receptor–deficient patients with or without hematopoietic stem cell transplantation(J)The Journal of Allergy and Clinical Immunology . 2012
  • 7Franke A,Mc Govern DP,Barrett JC,Wang K,Radford-Smith GL,Ahmad T,Lees CW,Balschun T,Lee J,Roberts R,Anderson CA,Bis JC,Bumpstead S,Ellinghaus D,Festen EM,Georges M,Green T,Haritunians T,Jostins L,Latiano A,Mathew CG,Montgomery GW,Prescott NJ,Raychaudhuri.Genomewide meta-analysis increases to 71 the number of confirmed Crohn’’s disease susceptibility loci. Nature Genetics . 2010
  • 8Mao H,Yang W,Lee PP,Ho MH,Yang J,Zeng S,Chong CY,Lee TL,Tu W,Lau YL.Exome sequencing identifies novel compound heterozygous mutations of IL-10 receptor 1 in neonatalonset Crohn’’s disease. Genes and Immunity . 2012
  • 9Levine Arie,Griffiths Anne,Markowitz James,Wilson David C,Turner Dan,Russell Richard K,Fell John,Ruemmele Frank M,Walters Thomas,Sherlock Mary,Dubinsky Marla,Hyams Jeffrey S.Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification. Inflammatory Bowel Diseases . 2011
  • 10Barrett JC,Hansoul S,Nicolae DL,Cho JH,Duerr RH,Rioux JD,Brant SR,Silverberg MS,Taylor KD,Barmada MM,BittonA,Dassopoulos T,Datta LW,Green T,Griffiths AM,Kistner EO,Murtha MT,Regueiro MD,Rotter JI,Schumm LP,Steinhart AH,Targan SR,Xavier RJ,Libioulle C,Sand.Genome-wide association defines more than 30distinct susceptibility loci for Crohn’’s disease. Nature Genetics . 2008

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