乳腺超声造影、弹性成像技术单独及联合诊断乳腺癌的临床价值

Clinical value of single contrast-enhanced ultrasound, ultrasonic elastography and combined detection of the two methods in diagnosis of breast cancer

目的 分析乳腺超声造影、弹性成像技术单独及联合诊断乳腺癌的临床价值.方法 将2017年1至2017年12月于南阳市中医院行乳腺肿块切除治疗的108例患者（137个乳腺肿块）作为研究对象.入选者均接受乳腺超声造影、弹性成像技术检查.观察超声造影、弹性成像技术诊断结果,并以病理诊断结果作为金标准,计算超声造影、弹性成像技术诊断乳腺癌的灵敏度、特异度与准确度.结果 经病理检查证实137个乳腺肿块中恶性肿块、良性肿块各48个、89个.以病理检查结果作为金标准,超声造影诊断乳腺肿块灵敏度、特异度与准确度分别为79.17％、80.90％、80.29％;弹性成像诊断乳腺肿块灵敏度、特异度与准确度分别为77.08％、82.02％、80.29％;超声造影、弹性成像联合诊断乳腺肿块灵敏度、特异度与准确度分别为95.83％、92.13％、92.75％.超声造影、弹性成像技术检测乳腺肿块灵敏度、特异度与准确度比较,差异未见统计学意义（P〉0.05）;较超声造影、弹性成像技术检查相比,超声造影、弹性成像技术联合检测乳腺肿块灵敏度、特异度与准确度相对较高,差异有统计学意义（P〈0.05）.结论 乳腺超声造影、弹性成像技术在乳腺癌诊断中具有一定应用的价值,但将其联合应用有助于提升乳腺癌的鉴别诊断效能.

Objective To analyze the clinical value of single contrast-enhanced ultrasound or combined with ultrasonic elastography in diagnosis of breast cancer .Methods A total of 108 patients with breast mass resection （137 breast masses ） in Nanyang Hospital of Traditional Chinese Medicine from January 2017 to December 2017 were selected , and they were given contrast-enhanced ultrasound and ultrasonic elastography examination .The diagnostic results of contrast-enhanced ultrasound and ultrasonic elastography were observed .The pathological diagnosis results were taken as the gold standard .The sensitivity , specificity , accuracy of contrast-enhanced ultrasound and ultrasonic elastography in diagnosis of breast cancer were recorded .Results Confirmed by pathological diagnosis , there were 48 malignant masses and 89 benign masses in 137 breast masses .The pathological results were taken as the gold standard , the sensitivity , specificity , accuracy of contrast-enhanced ultrasound in diagnosis of breast mass were 79.17％, 80.90％, 80.29％.The sensitivity , specificity , accuracy of ultrasonic elastography in diagnosis of breast mass were 77.08％, 82.02％, 80.29％.The sensitivity , specificity , accuracy ofcontrast-enhanced ultrasound combined with ultrasonic elastography in diagnosis of breast mass were 95.83％, 92.13％, 92.75％. There was no significant difference in the sensitivity , specificity , accuracy between contrast-enhanced ultrasound and ultrasonic elastography （ P〉0.05 ） .Compared with single contrast-enhanced ultrasound or ultrasonic elastography , the sensitivity , specificity , accuracy of contrast-enhanced ultrasound combined with ultrasonic elastography in diagnosis of breast mass were higher （ P〈0.05 ） .Conclusions Contrast-enhanced ultrasound and ultrasonic elastography in the＆nbsp;diagnosis of breast cancer have certain value , and the combined application can increase the diagnostic efficiency for breast cancer .