慢性病高风险人群体重和血脂干预效果评价

Effect of body weight and serum lipids interventions among high risk group with non-communicable diseases

目的 评价福田区慢性病高风险人群体重和血脂干预效果。 方法 2013年10—11月，通过简单随机抽样方法抽取12个社区，从中筛查出慢性病高风险人群1 923人，根据社区来源不同非随机分为干预组（ 1 338 人）和对照组（585人），干预组提供以健康生活方式指导为主的健康管理，对照组不主动采取任何形式干预活动。于2015年11-12月进行随访，采用倍差法评价体重和血脂干预效果。 结果 倍差法控制混杂因素后，干预2年后随访，干预组腰围、总胆固醇和低密度脂蛋白胆固醇分别下降1.929 cm、0.120 mmol/L、0.205 mmol/L，差异均有统计学意义 （ P 值均＜0.05）。 结论 以健康生活方式指导为主的健康管理，对慢性病高风险人群腰围、总胆固醇和低密度脂蛋白胆固醇等指标有一定程度的改善，可降低其慢性病的发病风险。

Objective To evaluate the effect of interventions on body weight and serum lipids among high risk group with non-communicable diseases （NCDs）. Methods A total of 12 communities were randomly selected from Futian district of Shenzhen city from Oct to Nov of 2013, 1 923 cases were identified as high risk group of NCDs, who were divided into intervention group （1 338 cases） and control group （585 cases）. The intervention group received group-based health education activities as intervention. No intervention was implemented in the control group. All participants were surveyed from Nov to Dec in 2015. The changes of weight and serum lipids were analyzed to examine the impact of intervention by difference method. Results After adjusting mixed factors of difference method, the follow-up study after 2 year-intervention showed that the waist circumference, total cholesterol and low density lipoprotein cholesterol levels of intervention group were reduced by 1.929 cm, 0.120 mmol/L and 0.205 mmol/L, respectively,all with significant difference（ all P 〈0.05）. Conclusion Health management guided by healthy lifestyle can obviously improve blood pressure, waist circumference, total cholesterol and low density lipoprotein cholesterol conditions among high risk group of NCDs and reduce the risk of disease occurrence.