布南色林工业化生产的研究

Study on Industrial Production of Blonanserin

通过工艺比较、选择和优化,确定出一条适合工业化生产的合成路线。以4-氟苯乙酮为起始原料,经取代、环合、酯化等操作得到布南色林。该工艺具有原料易得、操作简单、反应温度低和安全环保等优点。

By comparison,selection and optimization,we gain a suitable synthetic route for industrial production.4-Fluoroacetophenone as a starting material is made to Blonanserin,by substituted,cyclization,esterification and other operations.The process has easily obtained raw materials,simple operation,low reaction temperature and safety and environmental advantages.