颈动脉和冠状动脉粥样硬化的对比分析

Comparison of Carotid Artery and Coronary Atherosclerosis

动脉粥样硬化是一种全身系统性疾病。冠状动脉粥样硬化与颈动脉粥样硬化现已公认具有共存关系,然而这种关系的准确程度及强度尚未明确。冠状动脉粥样硬化预示着斑块破裂或侵蚀引发局部血栓的风险性,是心肌梗死的一大诱因。而临床案例表明心肌梗死患者也常伴发颈动脉硬化。与之类似,冠状动脉粥样硬化也普遍见于因严重颈动脉硬化导致血液灌注不足的脑卒中患者。可见,冠状动脉粥样硬化与颈动脉粥样硬化具有很多共同的风险因子(如年龄、糖尿病、高血压、吸烟和血脂异常等),在发病机制上,两种疾病有显而易见的差异,但又存在一定的联系。

Atherosclerosis is a systemic syndrome affecting arterial vessels in many parts of the body.A close relationship between carotid and coronary atherosclerosis was pointed out though the exact strength of this relationship is unclear and worth discussing.Coronary stenosis is a strong indicator for myocardial infarction,resulting from plaque rupture and the formation of local thrombosis.Patients with myocardial infarctions, are found to be at higher prevalence of carotid stenosis,as suggested by the clinical evidence.Similarly,coronary stenosis is also commonly found among stroke patients with insufficient blood infusion.It＇s obvious that they have a close relationship since they share some of the risk factors（e.g. age, diabetes ,hypertension,smoking,dyslipidemia） while they have apparent differences in the pathogenesis.