子午流注治疗对急性脑梗死患者运动功能及CD62P、TNF-α的影响

Effect of Ziwu Liuzhu therapy on motor function, CD62P and TNF-α in patients with acute cerebral infarction

目的探讨子午流注治疗对急性脑梗死患者运动功能及血小板膜糖蛋白微粒(CD62P)、肿瘤坏死因子-α(TNF-α)水平的影响。方法 60例急性脑梗死患者作为研究对象,随机分为对照组与观察组,各30例。对照组采用西医疗法联合神经促通技术(Bobath)进行治疗,观察组患者在对照组基础上加用子午流注技术进行治疗。对比两组患者临床治疗效果,治疗前后运动功能评分,治疗前后血液CD62P、TNF-α水平。结果观察组治疗总有效率为96.7%,高于对照组的80.0%,差异具有统计学意义(P<0.05)。治疗前,两组患者的运动功能评分对比,差异无统计学意义(P>0.05);治疗后,两组患者的运动功能评分均较本组治疗前升高,且观察组升高程度优于对照组,差异均具有统计学意义(P<0.05)。治疗前,两组患者的血液CD62P、TNF-α水平对比,差异均无统计学意义(P>0.05);治疗后,两组患者的血液CD62P、TNF-α水平均较本组治疗前降低,且观察组降低程度优于对照组,差异均具有统计学意义(P<0.05)。结论子午流注治疗模式在急性脑梗死患者临床治疗中效果显著,能够明显改善患者的运动功能,并有效降低血液中CD62P、TNF-α的水平,值得在临床上大力推广。

Objective To investigate the effect of Ziwu Liuzhu therapy on motor function, platelet membrane glycoprotein particles（CD62 P） and tumor necrosis factor（TNF-α） in patients with acute cerebral infarction. Methods A total of 60 patients with acute cerebral infarction as study subjects were randomly divided into control group and observation group, with 30 cases in each group. The control group received Western medical combined with neuro-promoting technology（Bobath） for treatment, and the observation group received Ziwu Liuzhu therapy on the basis of the control group. Comparison were made on clinical treatment effect, motor function scores, blood CD62 P, TNF-α levels before and after treatment between the two groups. Results The observation group had higher total treatment effective rate as 96.7% than 80.0% in the control group, and the difference was statistically significant（P〈0.05）. Before treatment, there was no statistically significant difference in motor function score（P〈0.05）. After treatment, the motor function scores of the two groups were higher than those before treatment, and the observation group was higher than the control group. Their difference was statistically significant（P〈0.05）. Before treatment, there was no statistically significant difference in blood CD62 P and TNF-α level（P〈0.05）. After treatment, the blood CD62 P and TNF-α level were lower than those before treatment, and the observation group was lower than the control group. Their difference was statistically significant （P〈0.05）. Conclusion Ziwu Liuzhu therapy shows a significant effect in the clinical treatment of patients with acute cerebral infarction, and this method can significantly improve the motor function of patients, as well as effectively reduce the level of CD62 P, TNF-α in blood. It is worthy of clinical promotion.