分化型甲状腺癌患者术后^(131)I治疗辐射并发症的防治研究

Prevention and treatment of radioactive complications of postoperative ^(131)I treatment for differentiated thyroid carcinoma

目的探讨分化型甲状腺癌患者术后采用核素^(131)I治疗辐射并发症的防治效果。方法选取2016年1月至2018年6月间湖北省十堰市人民医院收治的80例分化型甲状腺癌患者,均术后采用核素^(131)I治疗。针对常见并发症采用针对性用药、饮食和饮水等方案预防性治疗,分析防治处理后患者并发症发生状况。结果患者出现放射性腮腺炎1例,喉头水肿1例,骨髓抑制1例,胃肠道不适2例,发热6例,症状均较轻,采用针对性处理后,均未影响放疗进程。结论分化型甲状腺癌患者采用核素^(131)I对辐射并发症进行防治性处理,可有效降并发症发生。

Objective To investigate the efficacy of prevention and treatment of radioactive complications of radionuclide ^131I following surgery in patients with differentiated thyroid cancer. Methods A total of 80 patients with differentiated thyroid cancer who were treated with radionuclide ^131I after surgery at Hubei Medical College Affiliated People＇s Hospital between January 2016 and June 2018 were included. The patients were treated with specific medication,diet and drinking water,etc.,for targeted common complications. The incidence and survival were analyzed after the prevention and treatment of complications. Results Radioactive parotitis occurred in 1 patient,laryngeal edema occurred in 1 patient,myelosuppression occurred in 1 patient gastrointestinal discomfort occurred in 2 patients and fever occurredin 6 patients. All the symptoms were mild,and did not affect the course of radiotherapy after the treatment. Conclusion The prevention and treatment of complications in patients with differentiated thyroid cancer on radionuclide ^131I can effectively reduce the incidence of complications.