同种骨植入材料应用于颌骨缺损的临床效果观察

Clinical efficacy observation of allogenic bone material applied in jaw defect

目的同种骨植入材料加医用诱导骨基质应用于颌骨术后骨缺损,观察成骨效果的回顾性研究。方法颌骨手术患者43例,术后骨缺损直径2～5 cm,彻底清除病灶后植入同种骨植入材料及医用诱导骨基质,术后1周、1、3、6个月进行临床检查,术后6个月摄口腔全景片,根据临床症状及影像学结果评价术后感染率及术区骨质愈合情况。结果术区愈合不良率2.33%(1/43),6个月术区骨质愈合率88.37%(38/43)。结论同种骨植入材料加医用诱导骨基质具有良好的生物相容性,能够促进硬组织的形成,骨缺损修复临床效果好,术后疼痛、肿胀、感染率低。

Objective To observe the clinical effect of allogenic bone material and bone matrix in the treatment of bone defect after jaw surgery. Methods 43 cases of patients who underwent jaw surgery, with postoperative bone defect diameter 2-5 cm, were selected. After the complete removal of the lesion, allogeneic bone implant materials and medical bone matrix were implanted. Clinical examination was conducted 1 week, 1, 3, 6 months after surgery. Oral panoramic photos were taken 6 months after the operation. The postoperative infection rate and the bone healing in the operation area were evaluated according to the clinical symptoms and imaging findings. Results The rate of bad healing was 2.33% （1/43） , and the bone healing rate was 88.37% （38/43） in 6 months. Conclusion The same bone implant material and the medical induced bone matrix have good biocompatibility and can promote the formation of bone tissue, and have good clinical results, the postoperative pain, swelling and infection rate are low.