rTPA静脉溶栓联合动脉溶栓或支架取栓治疗急性缺血性脑卒中的临床效果

Clinical effect of intravenous thrombolysis of rTPA combined with arterial thrombolysis or stent embolectomy in the treatment of acute ischemic stroke

目的分析rTPA静脉溶栓联合动脉溶栓或支架取栓治疗急性缺血性脑卒中(AIS)的临床效果。方法选取我院2016年5月至2018年11月诊治的200例AIS患者作为研究对象,根据治疗方法的不同分为对照组和试验组,各100例。对照组接受动脉溶栓或支架治疗,试验组在此基础上联合静脉溶栓治疗。比较两组患者的治疗效果、并发症发生情况、治疗前后NIHSS评分。结果试验组患者的治疗总有效率高于对照组,并发症总发生率低于对照组(P<0.05)。治疗后,两组NIHSS评分均降低,且试验组低于对照组,差异有统计学意义(P<0.05)。结论 rTPA静脉溶栓联合动脉溶栓或支架取栓治疗AIS,可有效提高患者的治疗效果,降低并发症发生率和NIHSS评分,值得临床推广应用。

Objective To analyze the effect clinical of intravenous thrombolysis of rTPA combined with arterialthrombolysis or stent embolectomy in the treatment of acute ischemic stroke （AIS）. Methods A total of 200 patients with AIStreated in our hospital from May 2016 to November 2018 were selected as study objects, which were divided into controlgroup and experimental group according to different treatment methods, with 100 cases in each group. The control groupreceived arterial thrombolysis or stent treatment, and the experimental group combined with intravenous thrombolytic therapyon the basis of the control group. The treatment effects, incidence of complications, and NIHSS scores before and after treatmentwere compared between the two groups. Results After treatment, the total treatment effective rate of the experimental groupwas higher than that of the control group, and the total incidence of complications was lower than the control group（P〈0.05）.After treatment, the NIHSS scores of the two groups decreased, and that in the experimental group was lower than the controlgroup, the difference was statistically significant（P〈0.05）. Conclusion Intravenous thrombolysis of rTPA combined with arterialthrombolysis or stent embolectomy on AIS can effectively improve the treatment effect of patients, reduce the total incidence ofpost-stroke, and effectively decrease the NIHSS score. It is worthy of promotion in clinical practice.