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儿童急性淋巴细胞白血病复发相关基因突变的研究进展 被引量:3

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摘要 儿童急性淋巴细胞白血病(ALL)是儿童最常见的恶性肿瘤之一。随着大剂量联合化疗方案的不断改进,对危险因素的认识不断深入,基于危险因素的分层化疗的实施,以及支持治疗保障的提高,儿童ALL治疗效果得到了显著提高。发达国家儿童ALL的5年生存率可达90%以上,但仍有8%~20%患儿复发。ALL患儿首次复发后即使采取积极的增强化疗及异基因造血干细胞移植治疗,仅有少数患儿可以得到长期生存[1]。
作者 曾星 于洁
出处 《现代医药卫生》 2018年第23期3663-3666,共4页 Journal of Modern Medicine & Health
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