晚期妊娠合并重度子痫前期患者血栓弹力图检测分析

Clinical Characteristics of Thrombelastogram in Patients with Late Pregnancy and Severe Preeclampsia

目的:分析晚期妊娠合并重度子痫前期患者血栓弹力图(TEG)特点并与正常晚期妊娠孕妇比较。方法:选取江门市中心医院2015年7月至2017年6月期间收治的诊断妊娠晚期孕妇198例作为研究对象,其中正常晚期妊娠孕妇(100例)作为对照组,晚期妊娠合并重度子痫前期孕妇(98例)作为观察组。两组患者均在入院后、分娩前抽取肘正中静脉血,比较两组患者的TEG各参数检查结果。结果:两组患者TEG参数比较,其中观察组较对照组反应时间(RT)较大、凝固角(α)较小、凝血综合指数(CI)较小,差异具有统计学意义(P <0.05);组间凝血形成时间(K)、最大振幅(MA)比较,差异无统计学意义(P> 0.05)。结论:晚期妊娠重度子痫前期患者的凝血功能紊乱,借助TEG结果进行监测,能正确评估其凝血功能,最大程度降低围产期出血及栓塞性疾病的发生率,减少产妇不良事件发生的风险。

Objective To analyze the characteristics of thrombelastogram（TEG） in patients with advanced pregnancy combined with severe preeclampsia with normal late pregnancy. Methods 198 cases of pregnant women with late pregnancy were selected from Jiangmen Central Hospital from July 2015 to June 2017. Among them, pregnant women with normal late pregnancy（100 cases） served as the control group, and late pregnancy with severe preeclampsia pregnant women（98 cases） as the observation group. In both groups, the median venous blood of the elbow was taken after admission and before delivery, and the results of TEG parameters were compared between the two groups. Results The TEG parameters of the two groups were compared. The response time（RT） was larger, the angle α was smaller, and the coagulation index（CI） was smaller in the observation group（P〈0.05）. There was no significant difference in the K value and maximum amplitude（MA） between the groups（P〈0.05）. ConclusionCoagulation dysfunction in patients with severe preeclampsia in late pregnancy, with TEG results monitoring, can correctly assess its coagulation function, minimize the incidence of perinatal bleeding and embolic disease, and reduce the risk of maternal adverse events.