活血止痛散中乳香基原研究

Investigation on Origin of Frankincense in Huoxue Zhitong Powder

目的以活血止痛散为例,建立中成药中乳香基原的鉴别方法。方法采用显微和气相(GC)色谱技术对活血止痛散及其乳香原料进行比较研究。结果根据显微鉴别结果可首先排除印度乳香投料。GC鉴别结果显示所有样品均检出乙酸辛酯,均未检出α-蒎烯,表明企业均使用埃塞俄比亚乳香而非索马里乳香投料。结论所建方法操作简便、快速,可为类似制剂中乳香的质量控制提供参考。

Objective To establish a method for the identifcation of the origin of frankincense in traditional Chinese patent medicine, taking Huoxue Zhitong Powder as example. Methods Comparative investigation was conducted on Huoxue Zhitong Powder and the frankincense raw materials by microscopy and gas chromatography （GC） identification. Results India frankincense was ruled out first based on the results of microscopic identification. Then according to GC identifcation, octyl acetate rather than α-pinene was found in all samples, indicating that the manufactures used Ethiopic frankincense instead of Somali frankincense. Conclusion The proposed method is simple and fast, thus can provide reference for quality control of frankincense in similar drugs.