永远绽放的昙花——稳定卡宾发现史话

Nothing is Impossible: The Story of Discovering Stable Carbenes

卡宾一般作为化学反应中间体存在，性质极为活泼，寿命也极短，很难被制备分离出来。化学家们在探索了150多年后，才终于在1980年代末首次获得室温稳定的卡宾，但贝特朗的这一发现并没有得到化学界的普遍重视。1991年，阿杜恩戈首次分离出氮杂环卡宾，从而开启了稳定卡宾化学的新纪元。如今，稳定卡宾仍是化学中的重点研究领域。本文旨在回顾稳定卡宾的发现史，以加深人们对这一化学领域的了解。

Carbenes are highly reactive intermediates appearing transiently while some chemical reactions occur. The first stable carbene was obtained by G. Bertrand in 1988. However, the boom of stable carbene chemistry did not begin until the first N-heterocyclic carbine was isolated by A. J. Arduengo, III in 1991. This article aims to give an overview about the history of discovering stable carbenes.