白内障超声乳化术后局部用药治疗白内障患者干眼症的效果观察

Observation on effect of topical medication after cataract phacoemulsification on dry eye syndrome in cataract patients

目的探究白内障患者超声乳化术后干眼症采用局部用药治疗的临床效果。方法 86例行超声乳化术治疗的白内障患者,采用掷骰子法分为对照组和观察组,每组43例。对照组术后干眼症患者在常规治疗基础上加用聚乙烯醇滴眼液,观察组术后干眼症患者在对照组基础上加用玻璃酸钠滴眼液。比较两组患者术后早期干眼症发生情况、术后干眼症患者临床效果、干眼症患者泪膜破裂时间(BUT)、干眼症评分、角膜荧光染色评分。结果观察组术后早期干眼症发生率为30.23%,与对照组的32.56%比较差异无统计学意义(P>0.05)。观察组术后干眼症患者治疗总有效率为92.31%,高于对照组的57.14%,差异具有统计学意义(P<0.05)。术后1、4周,观察组术后干眼症泪膜破裂时间长于对照组,干眼症评分、角膜荧光染色评分均低于对照组,差异具有统计学意义(P<0.05)。结论白内障患者超声乳化术后容易出现干眼症,聚乙烯醇滴眼液、玻璃酸钠滴眼液联合用药的治疗效果显著,能够快速缓解干眼症状,改善视觉质量,在临床中值得大力推广应用。

Objective To investigate the clinical effect of topical medication after cataract phacoemulsification on dry eye syndrome in cataract patients. Methods A total of 86 cataract patients treated with phacoemulsification were divided by dice throwing method into control group and observation group, with 43 cases in each group. The control group was treated with polyvinyl alcohol eye drops on the basis of conventional therapy, and the observation group was treated with sodium hyaluronate eye drops on the basis of the control group. Comparison were made on early postoperative dry eye syndrome, clinical effect, tear film breakup time（BUT）, dry eye score, corneal fluorescence staining score of postoperative dry eye patients in two groups. Results The incidence of early dry eye in the observation group was 30.23%, which was not significantly different from 32.56% in the control group（P〉0.05）. The total treatment effective rate in observation group was 92.31%, which was higher than 57.14% in the control group, and the difference was statistically significant（P〈0.05）. At postoperative 1 and 4 weeks, the tear film break-up time in the observation group was longer than that in the control group, and the dry eye score and corneal fluorescence staining score in the observation group were lower than the control group. The difference was statistically significant（P〈0.05）. Conclusion After phacoemulsification, cataract patients are prone to dry eye syndrome. The combination of polyvinyl alcohol eye drops and sodium hyaluronate eye drops shows a remarkable treatment effect, and it can quickly relieve dry eye symptoms and improve visual quality. It is worth popularizing and applying in clinic.