碘甘油联合利多卡因对小儿疱疹性口腔炎患儿的临床效果研究

Study on clinical effect of iodine glycerol combined with lidocaine on children with herpetic stomatitis

目的采用碘甘油联合利多卡因治疗小儿疱疹性口腔炎患儿的临床效果。方法 78例疱疹性口腔炎患儿,采用随机数字表法分为对照组和治疗组,每组39例。对照组采用常规院内抗感染治疗,治疗组在对照组基础上加用碘甘油联合利多卡因治疗。对两组患儿的临床疗效及发热消退时间、疱疹消退时间、住院时间进行比较。结果对照组中显效15例,有效9例,无效15例,治疗总有效率为61.54%;治疗组中显效21例,有效14例,无效4例,治疗总有效率为89.74%;治疗组患儿的治疗总有效率显著高于对照组,差异具有统计学意义(P<0.05)。治疗组患儿的发热消退时间、疱疹消退时间、住院时间均明显短于对照组,差异具有统计学意义(P<0.05)。结论碘甘油联合利多卡因用于小儿疱疹性口腔炎,其治疗效果明显,缓解患儿口腔疼痛程度,病情得到较快好转,改善明显,在临床中值得应用。

Objective To discuss and compare the clinical effect of iodine glycerol combined with lidocaine on the treatment of children with herpetic stomatitis. Methods A total of 78 children with herpetic stomatitis were divided by random number table method into control group and treatment group, with 39 cases in each group. The control group was treated with routine hospital anti-infection treatment, and the treatment group was given iodine glycerin combined with lidocaine on the basis of the control group. Comparison were made on clinical efficacy, fever regression time, herpes regression time and hospitalization time between the two groups. Results The control group had 15 excellent cases, 9 effective cases and 15 ineffective cases, with total treatment effective rate as 61.54%, while the treatment group had 21 excellent cases, 14 effective cases and 4 ineffective cases, with total treatment effective rate as 89.74%. The total treatment effective rate of the treatment group was significantly higher than the control group, and the difference was statistically significant（P〈0.05）. The fever regression time, herpes regression time and hospitalization time in the treatment group were obviously shorter than the control group, and their difference was statistically significant（P〈0.05）. Conclusion Combination of iodine glycerin and lidocaine in children with herpetic stomatitis has obvious treatment effect, relieves the degree of oral pain in children, and the condition is improved faster and obviously. It is worthy of application in clinical practice.