食管癌靶向治疗研究进展

Advances in targeted therapy for esophageal cancer

食管癌是我国发病率最高的恶性肿瘤之一.其早期症状不明显,多数患者确诊时已属中晚期,丧失了手术时机,且对放化疗不敏感,预后较差,长期生存质量差.随着精准医学的到来,分子靶向治疗成为肿瘤治疗的一个重要发展方向,有关食管癌的很多靶向药物已经开始应用于临床.

Esophageal cancer is one of the most common malignant tumors in China .The early symptoms of this disease are not typical , so most patients are detected in the middle and advanced stages , resulting in missing the timing of surgery .Meanwhile , patients with esophageal cancer were not sensitive to radiotherapy and chemotherapy , with poor prognosis and poor long-term quality of life .With the development of precision medicine , molecular targeted therapy has became an important treatment method for esophageal cancer , and many targeted medicines have been used in clinic .