近10年代偿期乙肝肝硬化中医用药分析

Analysis of Traditional Chinese Medicine for the Treatment of Hepatitis B Cirrhosis in Recent 10 Years

目的:分析近10年(2007~2017)代偿期乙肝肝硬化的中医用药规律,为临床中医用药提供进一步参考。方法:通过文献的整理研究,将符合纳入标准的代偿期乙肝肝硬化中医和中西医证治文献中的药物进行归纳,对所用药物的类别、功效、药性、药味、归经进行统计分析。结果:在符合纳入条件的临床文献中,共涉及29首方剂,17类药物92味药,按归类使用频次排在前三位的是补虚药、活血化瘀药、清热药;按药物使用频次前三位分别为鳖甲、丹参、黄芪;药物性味归经使用频率较高的分别是温、寒、微寒,苦、甘、辛,肝、脾、肺经。结论:代偿期乙肝肝硬化中医治疗有其用药规律,本研究可为代偿期乙肝肝硬化的中医临床辨证用药提供循证学依据。

Objective To analyse the law of Chinese Medicine in the treatment of decompensated hepatitis B cirrhosis,and to provide further reference for clinical medicine. Methods Through the study of literature,the drugs in the literatures of TCM and Western medicine were summed up according to the standard of compensatory period,and the categories,efficacy,drug use,medicinal herbs,and the classification of drugs were analyzed statistically. Results Among the clinical literatures,29 prescriptions,17 types of drugs and 92 medicines were involved. According to the classification of the first three in the use of the drug,activating blood stasis drugs,heat-clearing drugs,according to the frequency of drug use of the first three before the turtle,Salvia miltiorrhiza,Radix astragali,the drug taste of the use of high frequency is temperature,cold,slightly cold,bitter,Gan,Xin,liver,spleen,lung meridian. Conclusion The TCM treatment of compensatory hepatitis B cirrhosis has its own law,this article can provide evidence-based basis for TCM clinical syndrome differentiation of the compensatory period of hepatitis B cirrhosis.