中国颅内动脉瘤患者的单中心流行病学研究

A single center epidemiological research on the patients with intracranial aneurysms in China

目的对本地区颅内动脉瘤的发病情况进行调查分析。方法对济宁市第一人民医院2012年10月1日至2016年4月30日经DSA诊断为颅内动脉瘤的426例患者进行流行病学调查,患者的性别、年龄人工统计,动脉瘤的大小、位置、数量通过DSA显示。结果本次调查共纳入男164例,女262例,男女比例(男/女) 0. 63,<39岁患者男女比例> 1,而≥70岁男女比例<0. 5,发病平均年龄男(55. 72±10. 77)岁,女(57. 91±9. 99)岁。该地区颅内动脉瘤发生的主要位置以颈内动脉(包括前交通动脉)为主,占总数的47. 18%,动脉瘤平均大小为(5. 4±3. 7) mm,颈内动脉动脉瘤发病的男女比例为0. 36,而大脑前动脉及大脑中动脉动脉瘤的发病男女比例趋近于1,多发动脉瘤占总人数的18. 08%。结论该地区颅内动脉瘤女性发病较男性晚,颅内动脉瘤发病率以颈内动脉为主,发病率的男女差异主要集中于颈内动脉(包括前交通动脉)动脉瘤的发病。

Objective To investigate and analyze the incidence of intracranial aneurysms in the local region.Methods The data about 426 patients who were diagnosed as intracranial aneurysms by digital subtraction angiography( DSA) in the first hospital of Jining City from October 1,2012 to April 30,2016 were epidemiologically analyzed. The gender and age of the patients were artificially statistically analyzed,and the aneurysmal size,location and number were displayed through DSA. Results There were 164 male patients and 262 female patients in this investigation. The ratio of males/females was 0. 63. The ratio of males/females in the age group of less than 39 years old was > 1,however,the ratio of males/females in the age group≥70 years was < 0. 5. The average age of onset in males was( 55. 72 ± 10. 77) years,which was( 57. 91 ± 9. 99) years in females. Moreover the main location of intracranial aneurysms was in internal carotid artery including the anterior communicating artery,which accounted for 47. 18%,and the average aneurysm size was( 5. 4 ± 3. 7)mm. The ratio of male/female was 0. 36 among the patients with internal carotid artery aneurysm,which was almost 1 among those with anterior cerebral artery and middle cerebral artery aneurysms. In addition the patients with multiple aneurysms accounted for 18. 08% of the total cases. Conclusion The onset of intracranial aneurysms in female patients is later than that in male patients. The incidence of intracranial aneurysms mainly is consisted of internal carotid artery aneurysm. The difference in the incidence of intracranial aneurysms between males and females is mainly in the incidence of internal carotid artery aneurysms including the anterior communicating artery.