颅脑创伤后脑死亡判定辅助技术的研究进展

Advance s in the research of assistive technology of brain death diagnosis after traumatic brain injury

颅脑创伤是神经外科临床常见病症,其中重型和特重型颅脑创伤的致死率很高。颅脑的原发性或继发性损伤,易导致颅脑结构和功能的严重受损,部分患者可进展为脑死亡,且颅脑创伤患者通常合并多发伤,因此临床中对于颅脑创伤患者脑死亡判定的准确性及可靠性要求越来越高。世界上多数国家脑死亡诊断主要依靠临床判定结合辅助技术,来进一步提高脑死亡判定的准确率。本文围绕脑死亡的概念、发展进程及脑死亡判定的几种辅助技术进行综述,以期为颅脑创伤后脑死亡的准确判定提供借鉴。

Traumatic brain injury （TBI） is a common clinical disease in neurosurgery, among which the mortality rate of severe and extra-severe TBI is very high. The primary or secondary TBI can easily lead to severe damage to the structure and function of the brain, some patients may develop into brain death. In addition, TBI patients are usually complicated with multiple injuries, so the accuracy and reliability of brain death diagnosis for TBI patients are increasingly required in clinic. Most countries in the world mainly rely on clinical diagnosis of brain death combined with assistive technology, which can further improve the accuracy of brain death diagnosis. In this paper, the concept, development and several assistive techniques of brain death diagnosis are summarized, so as to provide reference for the accurate diagnosis of brain death after TBI.