Binswanger病血液流变学及血液成份的观察

A study of hemorrhoelogy and blood components in patients with Binswanger disease

本文测定了３５例老年Ｂｉｎｓｗａｎｇｅｒ病患者的部分血液流变学及血液成份的变化。结果发现，与健康对照组和脑动脉硬化组比较，疾病组高切变率全血粘度显著升高，红细胞变形能力明显降低，血液成份ＨＧ、ＭＣＶ、ＭＣＨ、ＭＣＨＣ、ＲＤＷ显著增加。提示红细胞的老化性改变参与了Ｂｉｎｓｗａｎｇｅｒ病的发生，设法提高患者红细胞变形能力和降低血粘度将有益于阻止该病的进展。

Some blood hemorrheology and blood components indexes were measured in 35 patients with Binswanger disease, patients with cerebral arteriosclerosis and normal controls. The results showed that the whole blood viscosity at high shear rate. HGB, MCV, MCH, MCHC and RDW increased significantly and erythrocyte deformability decreased significantly when compared with normal control group and arteriosclerosis group. The data suggest that the aged changes of blood comPonents relate to the development of Binswanger disease, imProving erythrocyte deformability and reducing the whole blood viscosity is benifit to prevent deterioration of Binswanger disease.