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IPF1基因突变与胰腺发育不全和糖尿病

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出处 《四川医学》 CAS 2002年第9期970-971,共2页 Sichuan Medical Journal
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参考文献13

  • 1[1]Stoffel M,et al. Localization of human homeodomain transcription factor insulin promoter factor 1 ( IPF1 )to chromosome band 13q12.1. Genomics, 1995,28 : 125
  • 2[2]Ohlsson H,et al. IPF1,a homeodomain-containing transactivator of the insulin gene. EMBO J, 1993,12:4251
  • 3[3]Leonard J, et al. Characterization of somatostatin transavtivating factor-1,a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Molec Endocr, 1993,7:1275
  • 4[4]Miller C P,et al. IDX-1:a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostain gene. EMBO J, 1994,13: 1145
  • 5[5]Fiedored F T,et al. Mapping of the insulin promoter factor 1 gene (IPF1)to distal mouse chromosome 5. Genomics, 1995,28: 581
  • 6[6]Stoffers D A,et al. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nature Genet, 1997,15:106
  • 7[7]Stoffers D A,et al. Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein. J Clin Invest, 1998,102: 232
  • 8[8]Macfarlane W M,et al. Missense mutations in the insulin promoter factor- 1 gene predispose to type 2 diabetes. J Clin Invest, 1999,104:R33
  • 9[9]Hani E H,et al. Defective mutations in the insulin promoter factor-1(IPF1)gene in late-onset type 2 diabetes mellitus. J Clin Invest,1999,104:41
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