玻璃体腔注药治疗外因性眼内炎

Intravitreal administration of antibiotics in the treatment of exogenous endophthalmitis

目的 :评估玻璃体腔注药治疗外因性感染性眼内炎的疗效。方法 :回顾 1999年 7月～ 2 0 0 2年 2月我院收治的首诊时即给予玻璃体腔注药的外因性感染性眼内炎患者19例 19眼 ,平均年龄为 42 .4岁。其中白内障摘除联合人工晶体植入术后 5眼 ,眼球穿孔伤后 14眼。结果 :随访 5～ 35个月 ,玻璃体腔注药后炎症控制 9眼 ,治疗后视力在 0 .0 5以上者 8眼 ,有效率为 42 .1%。结论

Objective:To evaluate the therapeutic effect of intravitreal administration of antibiotics in the treatment of exogenous endophthalmitis.Methods:19 eyes of 19 patients were included in the study. 5 eyes developed postoperative intraocular infection and 14 eyes developed posttraumatic endophthalmitis. All patients were treated with intravitreal administration of antibiotics such as a combination of vancomycin and ceftazidime or clindamycin and amikacin or amphotericin B.Results:There was a 5～35 month follow-up period. Intraocular inflammation was controlled in 9 eyes and vision was better than 0.05 in 8 eyes after treatment,a successful treatment rate of 42%.Conclusion:Intravitreal administration of antibiotics was partially effective for exogenous endophthalmitis.