摘要
对四家工厂106名TDI接触工人的健康效应进行了连续三年动态观察,125名非接触工人做对照,并对车间空气中TDI浓度做了监测。调查表明,接触工人的呼吸、神经系统、粘膜刺激症状和体征较对照组明显增多,细胞免疫功能增强,血胆碱酯酶活性逐年降低;肺功能呈逐年下降趋势,且有剂量——效应关系。本文还对国家现行TDI空气卫生标准的可行性做了探讨。
A three year longitudinal study on the health effects of 106 TDI exposedworkers and 125 non-exposed controls in 4 plants were conducted.Theenvironmental concentrations of TDI were monitored during the period of ob-servation.An excess of respiratory and neurological manifestations,a slightenhancement of cell mediated immunity and an inhibition of bloodcholinesterase activity were revealed among TDI exposed groups comparedwith thosed in control group.An annual decline in pulmonary functions and adose-effect relationship between changes and TDI exposure levels were alsomanifested.The feasibility of the current national air standard foroccupational exposure to TDI was here discussed.
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
1991年第5期285-289,共5页
Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词
二异氰酸
TDK
工人
危害
Toluene
Diisocyanate
(TDI)
Health effects
Puhnonary functions cholinesterase activity.
