阿普唑仑治疗功能性消化不良的疗效研究

A clinical study of treatment on functional dyspepsia with Alprazolam

目的 观察功能性消化不良 (FD)患者 ,在使用抑酸剂和促进胃动力药治疗的基础上加用阿普唑仑后的疗效及对各型FD的疗效。方法 将我院门诊的 1 92例FD患者随机分成两组。实验组 1 2 6例用法莫替丁、吗叮啉、阿普唑仑治疗 ;对照组 66例用法莫替丁、吗叮啉治疗 ;分别观察他们的疗效。并对实验组进行分型 ,观察对各型FD的疗效。结果 实验组总有效率为 86 51 % ,对照组总有效率为 69 70 % ,两组总有效率间的差别有显著性意义 (P <0 0 1 ) ;实验组各分型的疗效间差别有显著性意义 (P <0 0 1 )。结论 在使用抑酸剂和促进胃动力药的基础上加用阿普唑仑治疗FD 。

Objective To observe the curative effect of Alprazolam in treating Functional Dyspepsia(FD),on the bases of antacids and promoter kinetic drug,and to compare the effect on different types of FD.Methods 192 cases were randomly divided into two groups.The experiment group (n=126) was treated with Famotidine,Motilium and Alprazolam,the control group was treated with Famotidine and Motilium.The effect on FD were observed in two groups.At the same time the experiment group was divided different types and their effects were observed.Results The total effective rate in the control group was 69 70% and 86.51% in the experiment group,there was significant differences in the total effective rate between two groups(P<0 01).There was significant difference in the total effective rate among all types in experiment.Conclusion Using Alprazolam in treating FD besides antacids and promoter kinetic drug can improve the effect apparently.