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T细胞表位的确定 被引量:2

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摘要 确定抗原分子被T细胞所识别抗原分子上的短肽序列,对T细胞表位进行定位对于特异性免疫应答的调节有重要意义。由于CD4^+T细胞表位和CD8^+T细胞表位在各方面性质的诸多不同,对这两种表位进行定位所采取的策略也应该是不同的。运用所选择的效应细胞对合成肽库的筛选是对CD4^+T细胞表位进行定位的有效策略,而对于CD8^+T细胞表位定位,需要通过一些特殊的手法将抗原肽导入细胞后进一步运用效应细胞进行筛选。
作者 周洪
出处 《细胞生物学杂志》 CSCD 北大核心 2002年第4期196-199,共4页 Chinese Journal of Cell Biology
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参考文献18

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同被引文献19

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