摘要
目的 :探讨溃疡性结肠炎的微生态学改变及双歧杆菌对溃疡性结肠炎的预防和治疗作用。方法 :以 Western大白鼠为模型。结果 :发生溃疡性结肠炎时动物体重、双歧杆菌活菌计数、G+ / G-菌相对数均发生显著性降低 (P>0 .0 1) ,且伴随相关体征、结肠肉眼观察及病理切片检查的恶性改变 ;对照组及预先双歧杆菌灌肠 1周后再行诱导组差异无显著性 (P<0 .0 5 )。结论 :双歧杆菌与常规药物均对溃疡性结肠炎有明显的治疗作用 ,但双歧杆菌治疗作用疗效好于常规药物疗法 。
Objective:To the microecological changes and the prevention and therapy by using Bifidobacterium of ulcerative colitis.Methods:Through western rat model.Results:When ulcerative colitis occurs,the weight, Bifidobacterium ,the relative count of the G + bacteria will decrease deeply( P <0 01) companied with the malignant changes of the ulcerative colitis concerned features and the observation under eyes and microscope of the colon.Whereas the contrast and preventional animals have no prominent changes( P <0 05).Conclusion:The rontine method and treatment by using Bifidobacterium both have effects in curing the disease,but treatment by using Bifidobacterium both have effects in curing the disease,but treatment by using Bifidobacterium is better and treatment by adjusting the microecology is a new and better method.
出处
《中国微生态学杂志》
CAS
CSCD
2002年第4期199-203,共5页
Chinese Journal of Microecology
关键词
溃疡性结肠炎
微生态学研究
防治
Ulcerative colitis
Bifidobacterium
Prevention
Treatment
