3种消毒剂对肠道致泻菌最小杀菌浓度的测定

MEASUREMENT OF MINIMUM BACTERICIDAL CONCENTRATIONS OF 3 DISINFECTANTS AGAINST INTESTINAL BACTERIA CAUSING DIARRHEA

为对防制感染性腹泻的消毒工作提供依据,用悬液定性杀菌试验,测定了稳定性二氧化氯、过氧戊二酸、氯己定对从临床分离的肠出血性大肠杆菌O157:H7和3株气单胞菌作用1min和10min的最小杀菌浓度。结果,二氧化氯作用1min和10min杀灭所试菌的最低浓度分别为≥920mg/L和≥701mg/L;过氧戊二酸者分别为≥5500mg/L和≥5170mg/L; 氯己定者分别为≥9000mg/L和≥792mg/L。说明所试3种消毒剂对4株临床分离到的肠道致泻菌均有良好杀灭作用。

In order to provide basis for disinfection in prevention of infectious diarrhea, quantitative suspension germicidal test was used to measure the minimun concentrations of stable chlorine dioxide, perglutaric acid and chlorhexidine for killing clinical isolates of enlerorrhagic Escherichia coli O157 : H7 and 3 strains of Aeromonas in 1 min and 10 min. The results showed that the minimum concentrations of chlorine dioxide for killing the bacteria tested in 1 min and 10 min were ≥920 mg/ L and ≥701 mg/ L respectively, those of perglutaric acid were ≥5 500 mg/ L and 5 170 mg/ L respectively and those of chlorhexidine were ≥9 000 mg / L and ≥792 mg / L respectively, indicating that the 3 disinfectants tested have good germicidal efficacy in killing 4 strains of intestinal bacteria causing diarrhea isolated clinically.