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免疫抑制剂他克莫司在肾脏移植的应用 被引量:3

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摘要 目的 :对免疫抑制剂他克莫司在肾脏移植应用的进展进行综述。方法 :综述近年来他克莫司在肾脏移植应用的有关文献。结果 :他克莫司具有极强的免疫抑制作用 ,可以降低移植肾早期急性排斥反应的发生率 ,但现有临床资料显示它并不能延长移植肾的中长期存活期。和环孢素相比 ,他克莫司治疗的病人高血压和高脂血症的发生率较低 ,但神经并发症和糖尿病发生率高。结论 :他克莫司是一种有效的免疫抑制剂 ,可用于肾脏移植的基础治疗和转换治疗 。
作者 杜斌 薛武军
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2002年第9期546-547,共2页 Chinese Journal of Hospital Pharmacy
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