能谱CT对肺内占位良恶性鉴别及诊断价值

Identification and Diagnostic Value of Energy Spectrum CT for Benign and Malignant Pulmonary Lesions

目的探讨能谱CT对肺内占位良恶性的鉴别及诊断价值。方法选择我院2015年3月至2017年10月经影像学检查(X线、CT)发现肺内占位的57例患者作为研究对象,根据病理检查结果将其分为良性占位组(n=21)和恶性占位组(n=36)。两组患者均实施能谱CT成像技术,并对图像进行分析处理,对比两组动、静脉期40-80keV隔间单能量CT值,动脉期40-70keV期间能谱斜率,动、静脉期碘和水基值及差值。结果动、静脉期40-80keV隔间单能量CT值及动脉期40-70keV期间能谱斜率,良性占位组均低于恶性占位组,差异有统计学意义(P<0.05)。动、静脉期碘基值及差值,良性占位均低于恶性占位,差异有统计学意义(P<0.05);动、静脉期水基值及差值,良性占位均高于恶性占位,差异有统计学意义(P<0.05)。结论肺内占位良恶性在能谱CT表现上存在一定差异,其诊断结果对临床诊断具有一定参考价值。

Objective To explore the identification and diagnostic value of energy spectrum CT for benign and malignant lung lesions. Methods A total of 57 patients with pulmonary lesion examined by X-ray and chest CT from March 2015 to October 2017 were selected for the study. According to the pathological examination results, the patients were divided into benign lesion group(n=21) and malignant lesion group(n=36). The two groups were given energy spectrum CT imaging technique, and the images were analyzed and processed. The single-energy CT values of 40-80 keV compartments in arterial and venous phases, and the energy spectrum slope of 40-70 keV compartments in arterial phase, iodine base value and water base value and difference in arterial and venous phases were compared between the two groups. Results The single-energy CT values of 40-80 keV compartments in arterial and venous phases were lower in benign lesion group than those in malignant lesion group(P<0.05). There was a statistically significant difference in the energy spectrum slope of 40-70 keV compartments in arterial phase(P<0.05). The iodine base value and difference in arterial and venous phases were lower in benign lesion group than those in malignant lesion group(P<0.05). The water base value and difference in arterial and venous phases were higher in benign lesion group than those in malignant lesion group(P<0.05). Conclusion There are some differences in the energy spectrum CT findings of benign and malignant lung lesions. CT diagnostic results have certain reference value for clinical diagnosis.