摘要
目的:观察辛伐他汀在治疗不稳定心绞痛的治疗作用。方法:将60例不稳定心绞痛患者随机分为治疗组(30例)和对照组(30例),在常规治疗基础上治疗组每晚睡前加服辛伐他汀40mg,8周后观察临床疗效及血脂变化。结果:治疗组治疗后血清胆固醇(TC)及低密度脂蛋白胆固醇(LDL-C)水平明显下降(P﹤0.05),甘油三酯(TG)水平轻度下降,高密度脂蛋白胆固醇(HDL-C)水平轻度升高,治疗组临床症状明显改善,与对照组比较具有显著性差异(P﹤0.05)。结论:辛伐他汀具有调脂作用,对不稳定心绞痛治疗有显著疗效,可改善预后,在临床上具有较大的实用价值。
Objective:To evaluate effects of simvastatin for the treatment of unstable angina pectoris(UAP).Methods Sixty patients with UAP were randomly divided into control group(with conventional therapy,n=30) and simvastatin group(with conventional therapy and simvastatin 40mg before retiring,n=30),the therapeutic effects and serum lipids variation were assessed after 8 weeks.Results In simvastatin group,the levels of serum total cholesterol(TC) and lower density lipid cholesterol(LDL-C) decreased significantly,triglyc-erides(TG) decreased lightly,higher density lipid cholesterol(HDL-C) increased lightly,clinical symptom improved significantly com-pared with the control group(P﹤0.05),but there was no significant change in control group(P﹤0.05).Conclusion Simvastatin can regulate the serum lipids,the therapeutic effects are significant and improve prognosis in the treatment of UAP.
出处
《内蒙古中医药》
2008年第10X期3-4,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
辛伐他汀
治疗
不稳定心绞痛
Simvastatin
Treatment
unstable angina pectoris
