乙型肝炎病毒母婴传播相关因素Logistic回归分析

The Logistic Regression Analysis of Relevant Effectors of Maternal-Infant Transmission of Hepatitis B Virus

目的:评价乙型肝炎病毒母婴传播相关因素。方法:对207例孕妇孕期包括一般情况、家族肝病史、孕期肝功检测、是否进行治疗、有否进行孕晚期高效价乙型肝炎病毒免疫球蛋白母婴阻断治疗、孕晚期并发症、分娩方式、乳汁HBV-DNA检测、新生儿脐带血HBV-DNA检测等进行调查统计。婴儿七个月血清HBV-M检测结果作为是否阻断成功的依据,应用Logistic分析来评价影响乙型肝炎病毒母婴传播的相关因素。结果:在上述多种因素中,只有孕晚期是否进行乙型肝炎病毒母婴阻断是影响母婴传播的因素。结论:对乙型肝炎病毒携带孕妇孕晚期进行高效价乙型肝炎病毒免疫球蛋白母婴阻断治疗是有重要意义的。

Objective:To evaluate the relevant effectors of maternal-infant transmission of hepatitis B virus(HBV).Methods:The statistic inquiry was done in 200 pregnant women including personal information ,the family data , the liver function ,the data of treatment of maternal-infant interruption,the mode of delivery,the detection of HBV of maternal milk and blood of umbilical cord.The result of HBV-M of the baby of 7 month old as the dependent to do the logistic regression.Results:In so many variables only the treatment of maternal-infant interruption is meaning.Conclusions:It is significant to do the maternal-infant transmission by HBV immunoglobulin to pregnant woman combined with HBV infection.