渗出型老年黄斑变性患者眼底相干光断层成像结果分析

Characteristics of optical coherence tomography for exudative age-related macular degeneration

目的 了解渗出型老年黄斑变性 (age relatedmaculardegeneration ,AMD)患者的眼底相干光断层成像 (opticalcoherencetomography ,OCT)特征。方法 对经常规检查、荧光素眼底血管造影(fundusfluoresceinangiography,FFA)、吲哚青绿脉络膜血管造影 (indocyaninegreenangiography ,ICGA)确诊的渗出型AMD患者 38例 (42只眼 )行眼底OCT检查 ,分析其图像资料 ,并与其FFA和ICGA检查结果进行比较。结果 OCT图像特征 :典型纤维性新生血管膜 34只眼 ,浆液性视网膜神经上皮脱离 38只眼 ,视网膜神经纤维层脱离合并层间水肿 8只眼 ,出血性和浆液性视网膜色素上皮 (retinalpigmentepithelium ,RPE)脱离分别为 11只眼和 9只眼。结论 渗出型AMD患者眼底OCT图像特征为典型的纤维性新生血管膜合并浆液性视网膜神经上皮脱离、视网膜神经纤维层脱离、浆液性和出血性RPE脱离。上述图像特点证实和补充了FFA和ICGA检查结果 ,有助于渗出型AMD的诊断和评价。

Objective To observe the characteristics of optical coherence tomography (OCT) for exudative age related macular degeneration (AMD). Methods Thirty eight patients (42 eyes) diagnosed as exudative AMD by color fundus photography, fundus fluorescein angiography(FFA) and indocyanine green angiography (ICGA) were examined by OCT. The results of OCT were analyzed and compared with that of FFA and ICGA. Results The characteristics of OCT for exudative AMD: fibrotic choroidal neovascularization (34 eyes), serous detachment of neurosensory epithelium (38 eyes), detachment of the nerve fiber layer (8 eyes), and hemorrhagic and serous detachment of retinal pigment epithelium (11 eyes and 9 eyes, respectively). Conclusion The major characteristic of OCT of exudative AMD is fibrotic choroidal neovascularization combined with serous and hemorrhagic detachment of neurosensory epithelium or retinal pigment epithelium, which would be helpful for diagnosing and evaluating exudative AMD.