1999年～2001年上海市医院抗组胺药应用分析

Analysis of the Use of Antihistamine Agents in Hospitals of Shanghai During the 1999～2001 Period

目的 :分析上海市医院抗组胺药的应用情况 ,供生产、营销、应用等部门参考。方法 :调查上海市47家医院1999年～2001年抗组胺药主要品种、用量、金额、DDDs以及临床的评价和不良反应。结果与结论 :抗组胺药品种变化不大 ,用量2001年有所下降 ,目前最常用的为西替利嗪、氯雷他定和酮替芬等。报道的心脏毒性发生率虽然极低 ,亦应警惕。

OBJECTIVE:To analyse the situation of use of antihistamine agents in hospitals of Shanghai and to make objective evaluation as reference for production,sale and consumption departments METHODS:To investigate the antihistamine agents used in 47 hospitals of Shanghai during the 1999～2001 period in respect to the kinds,dosage sum of money of consumption,DDDs,clinical evaluation and ARDs RESULTS & CONCLUSION:Consumption of antihistamine agents decreased in 2001,but kinds of drugs had no obvious change The commonly-used antihistamine agents were Cetirizine,Loratadine and Kitotifen Incidence of cardiotoxicity is very low,but we must take care of it