急性上尿路梗阻全身炎症反应综合征76例临床分析

Clinical study on systemic inflammatory response syndrome in 76 patients with acute upper urinary tract obstruction

目的 :提高对急性上尿路梗阻全身炎症反应综合征 (SIRS)与多器官功能障碍综合征 (MODS)关系的认识 ,探讨MODS的防治策略。方法 :分析 76例急性上尿路梗阻患者SIRS的临床资料及MODS发生率。结果 :入院时出现SIRS者 2 1例 ,发生率 2 7.6 % ,其中 8例发生MODS(38.1% ) ,MODS中 3例死亡。结论 :MODS中急性肾功能衰竭最常见 ,随着符合SIRS标准项目的增加 ,病死率比例也增加 (P <0 .0 5 )。早期诊断SIRS ,积极治疗机体炎症反应 ,及时解除上尿路梗阻 。

Purpose:To analyze the relation between systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) and investigate the therapeutic strategy.Methods:The clinical data of 76 patients accepted by our hospital from January 1998 to July 2001 were analyzed.Results:21( 27.6%) of the 76 patients were diagnosed SIRS, afterwards the 8 patients( 38.1%) suffered from MODS and the mortality of the patients with SIRS was 14.3%(3/76). The most common syndrome was renal function failure. The mortality of patients increased with the number of SIRS criteria that the patients encountered. There was statistical significance (P< 0.05).Conclusion:The upper urinary tract obstruction patients accompanied by SIRS should be diagnosed early and it is important to remove the body's obstruction as soon as possible.