轻度认知障碍和老年性痴呆关系的研究

The study of the relation between mild cognition impairment and Alzheimer disease

目的 研究轻度认知损害 (MCI)和老年痴呆 (AD)发病关系。方法 应用MMSE、ADL、HIS神经心理量表评价记忆和认知 ,检测血液生化、ESR、TSH。常规头部CT或MCI检查 ,必要时神经电生理检查。结果 研究提示12 %MCI患者在 1年内 ,2 3 %在 2年内 ,3 2 %在 3年内 ,5 0 %患者在 4年内进展为AD。结论 MCI是AD发病的预警信号 ,如果能早期筛选出MCI患者 ,进行预防性干预 。

Objective To study the relation between mild cognition(MCI) and alzheimer disease(AD). Methods MMSE?ADL?HIS and neunopsychology Liagrams were applied to evaluate memony and recognition, ESR, TSH and biochemistry of blood were also determined Results This study revealedthat 12% of MCI patients in one year, 23% of patients in two years, 32% in three years and 50% patients in four years had develoded into AD. Conclusions It is concluded that MCI is a sign of coming AD. Ifwe can select out MCI patients in its early Stage and take proper perventive mean, which will surely helps to improve the patients'living Quality.