以胎儿睾丸为移植体的睾丸移植六例报告

Testis transplantation with fetal testis as donor for treatment of male hypogonadism

目的 探讨胎儿睾丸移植在男性性腺功能减退症治疗中的临床应用价值。方法 利用胎儿睾丸作移植体 ,为 6例男性性腺功能减退症患者施行了胎儿睾丸移植术。结果 术后 5个月 ,6例患者的血清睾酮水平明显升高 ,性欲、性功能及第二性征明显改善 ,移植睾丸体积较术前增大。结论 胎儿睾丸移植治疗男性性腺功能减退症是有效的 ,且胎儿睾丸免疫原性低 。

Objective To investigate the value of the clinical application of fetal testis for the treatment of male hypogonadism.Method We have performed the testicular transplantation to cure 6 patients suffered from hypogonadism with the fetal testis as donor.Results All patients had a significantly increased level of serum testosterone and the male secondary sexual characteristics and the sexual desire were improved.The size of testis was larger than before operation.Conclusion Testis transplantation with fetal testis as donor is an effective method to cure male hypogonadism and has great value of clinical application for its weak immunogenicity.