摘要
报告1985～1988年我所烧伤感染常见菌及其对抗生素敏感性的变化,结果表明,在烧伤感染常见菌中,革兰氏阴性杆菌63.9%仍然多于革兰氏阳性球菌40.5%.在革兰氏阴性杆菌中,绿脓杆菌仍居首位(28.5%),变形杆菌跃居第二位9.1%;在革兰氏阳性球菌中,金黄色葡萄球菌32.8%,居总检出菌的第一位。从敏感试验结果看,不论是革兰氏阴性杆菌,还是革兰氏阳性球菌,对我所常用抗生素的抗药菌株都逐年增加.
This paper reports common pathogens in burn infection and changes in their drug sensi- tivity from 1985 to 1988.Gram negative rods constituted 55.7% of all pathogens,while 40.5% were gram positive cocci.The former group consisted of 173 strains of Pseudomonas aerugino- sa(28.5%),55 Proteus(9.1%),33 Serratia(5.4%),23 Klebsiella(3.8%)19,Acinetobacter (3.1%),18 Enterobacter(3.0%)and 17 E.coli(2.8%). Among gram-positive cocci,Staphylococcus aureus accounted for 32.8%,Staphylococcus epidermidis accounted for 5.6%,and Streptococcus faecahs accounted for 2.1%. All the gram-negative rods and gram-positive cocci showed more resistance against vari- ous antibiotics.Ps.aeruginosa were resistant to 24 commonly used antibiotics.However,cip- rofloxacin,ceftaztdime and piperacillin were comparatively effective,the sensitivity rates were 92.9%,91.5% and 78.3%,respectively.Ps.aeruginosa showed a sensitivity rate of 92.5% and 86.1% to amikacin and polymyxin-B,respectively,from 1980 to 1984,but the rates were lowered to 65.9% and 17.3%,respectively,from 1985 to 1988. Staphoylcoccus aureus showed a sensitivity rate of 88.9% to ciprofloxacin,76.1% to ceftazidime,71.4% to amikacin,48.5% to piperacillin,63.1% to cefuroxime.This organism showed a sensitivity rate of 87.3%,83.9%,81.7% and 82.8% to amikacin,cefoperozone, leucomycin and lincomycin,respectively,from 1980 to 1984,but the sensitivity rates dec- lined to 71.4%,56.8%,60.8% and 43.7%,respectively,from 1985 to 1988.
