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微流控芯片与生物质谱联用技术的发展与展望 被引量：2

The Development and Foreground of Microfluidic Device Coupled to Bio-Mass Spectrometry
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摘要 本文系统归纳了当前微流控电泳芯片与生物质谱的联用模式。芯片材质涵盖玻璃与高聚物 ,与接口衔接的电离手段包括电喷雾电离 ( ESI)和基质辅助激光解析电离 ( MAL DI)。 Microfluidic devices have been coupled to mass spectrometers (MS) though their dimensions seem unlikely for marriage. Three types of interface designs are concluded for MS with electrospray ionization while some novel means is also reported to couple microchip to MALDI-TOF. The substrate of microfluidic devices cover both glass and plastic. Various integrated protein preparation and preconcentration procedures together with its trend toward multiplexing are also reviewed.
作者 水雯箐 苏佳 黄珍玉 黄懿 杨芃原
机构地区 复旦大学化学系
出处 《质谱学报》 EI CAS CSCD 2002年第2期100-111,99,共13页 Journal of Chinese Mass Spectrometry Society
关键词 联用技术 发展 微流控芯片 生物质谱 电泳芯片 生物大分子 分析 microfluidic device micro chip bio-mass spectrometry development and foreground
分类号 Q503 [生物学—生物化学] O657.63 [理学—分析化学]
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参考文献37

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同被引文献57

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质谱学报
2002年 第2期

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