疏肝化瘀颗粒治疗慢性乙型肝炎和肝炎肝硬化的临床研究

Therapeutic Effect of Shugan Huayu Granule on Chronic Hepatitis B and Post hepatitic Cirrhosis

目的:研究疏肝化瘀颗粒对慢性乙型肝炎和肝炎肝硬化的治疗作用。方法:用疏肝化瘀颗粒治疗慢性乙型肝炎和肝炎肝硬化病人76例,疗程为3～6个月。观察肝功能、肝纤维化指标、B超声像图及肝脏储备功能的变化,对各组检测结果进行比较。结果:治疗组在降低丙氨酸转氨酶、门冬氨酸转氨酶,提高血清白蛋白及肝脏的储备功能,降低血清肝纤维他指标等方面均明显优于对照组。结论:疏肝化瘀颗粒具有明显改善肝功能和抗肝纤维化的作用,临床应用未发现毒副作用,是临床治疗慢性乙型肝炎和肝炎肝硬化的有效药物。

Objective: To study the therapeutic effect of Shugan Huayu granule on chronic hepatitis B and posthepatitic cirrhosis. Methods: Using Shugan Huayu granule treated 76 cases of chronic hepatitis B and posthepatitic cirrhosis for 3-6 months, the items of liver were assayed in all patients and contrasted among various groups. Results: Therapy group were more significant than control group in lowering the serum level of ALT, ASTand markers of hepatic fibrosis, raising the level of serum albumin and reserve function of liver. Conclusion: Shugan Huayu granule has significant effect in improving hepatic function and liver fibrosis. There are not toxic and side effect. It is a effective drug on the treatment of chronic hepatitis B and posthepatitic cirrhosis.