成都地区高脂血症调查分析(附7288例报告)

Epidemiological Survey (1999-2000) of Hyperlipidemia in Chengdu Area (7288 Cases Analysis)

目的 了解成都地区人群当前血脂水平,高脂血症患病率及其影响因素。方法 整群抽样7288人,均居住3年以上,年龄18-80岁,调查一般人口统计学指标,烟酒嗜好,人均收入,个人及家族史,查血压,心率,体重指数及血液有关生化参数。结果 本组人群甘油三酯平均1.50mmol/L,随年龄增加,总胆固醇平均4.89mmol/L,高密度脂蛋白平均1.35mmol/L.甘油三酯≥1.70mmol/L者24.99％,≥2.3mmol/L者为13.4％,高密度脂蛋白<0.91mmol/L者为8.29％,混合性高脂血症(胆固醇≥5.2,甘油三酯≥2.3mmol/L者)有9.5％,双变量相关分析,胆固醇与甘油三酯与年龄,BMI,血糖,尿酸,舒张压,饮白酒,显著相关。与吸烟指数,心率,收缩压相关较弱。多变量逐步回归,甘油三酯与BMI,尿酸,饮酒及胆固醇,胆固醇与年龄,甘油三酯,高密度脂蛋白,血糖,BMI仍相关。结论 近年来成都地区血脂水平及高脂血症患病率均有明显增高,改善生活方式与一期预防是当务之急。

Objective Dislipidemia is a well known cardiovascular (CV) risk factor. Prevalence of dyslipidemia has been changed dramatically during last 20 years. We conducted a survey aimed to evaluate the level of CV risk factor and it's relative factor in the population of Chengdu, China. Methods In this population-based survey, 7288Chengdu residents, both sexes aged 18-80 years were included. The population statstical parameters, habits, income, history, physical and laboratory examination for all these people were collected and analyzed. Results For all these people,mean total cholesterol (TC) is 4. 89mmol/L, with a mean triglyceride level of 1. 50mmol/L, and mean HDL of 1. 35mmol/L. According to the criteria of dislipidemia, in this surveyed population, there were 34.6%, 17. 97% and 8. 98% people, respectively, whose TC≥5. 2, 5. 72 and 6. 2mmol/L. Besides, there were 25% and 13. 4% people, whose TG≥1. 7 and 2. 3mmol/L, respectively. And there were 8. 47% people, whose HDL<0. 91mmol/L. There were 9. 5% subjects with mixed hyperlipidemia. The subjects of hyperlipidemia co-existed with a higher prevalence of hypertension and impaired glucosemetabolism and some of other risk factors. Conclusions The results of this survey suggested that the mean lipid level, and prevalence of dyslipidemia were increased during last 2 decades in population of Chengdu. These dyslipidemia clustering with hypertenson, diabetes, overweight. It means that in the next 10-20 years the CVD might be a serious challenge for this population.