环丙沙星治疗小儿急性菌痢60例疗效观察

The observing of curative effect with clprofloxacin(CPFX) in 60 cases with acute bacillary dysentery

目的 观察环丙沙星治疗小儿急性菌痢的临床疗效。方法 60例采用环丙沙星 (CPFX)口服(30mg·kg- 1 ·d- 1 )治疗 ,同期吡哌酸 (PPA)口服 (30mg·kg- 1 ·d- 1 )治疗 60例作对照 ,疗程均为 3～ 5d。结果 CPFX组在疗程内全部治愈 (1 0 0 % ) ,PPA组仅部分治愈 (2 3 3 % )。体温恢复正常时间 ,腹痛、腹泻、脓血便消失时间 ,大便镜检复常时间 ,住院天数等 ,CPFX组明显优于PPA组。结论 环丙沙星治疗小儿急性菌痢疗效显著。

Objective To obserce clinical efficiency of ciprofloxacin to treat children's acute bacillary dysentery.Methods In this paper,the authors reported 60 patients(the age being 1～10 years old) with acute bacillary dysentery were treated orally with CPFX(300 mg·kg -1 ·d -1 ),and the other 60 cases with pipernidic acid(PPA,30 mg·kg -1 ·d -1 ) as a control group in 3～5 days each.Results The results showed that the supmplom,such as fever,abdominal pain,diarrhea and blood and pus in stool in the experimental group disappeared more quickly than that of the control group.The course of treatment with CPFX was markedly short and the cure rate was 100% and 23.3% in the experimental group and control group respeclively.Conclusion The response to CPFX is better than that to PPA in patients with acute bacillary dysentery in the short term therapy without obvious side effect.